Rapid changes in information technologies have lead to a boost in the strength and efficiency of human activity. These technologies have an influence on every area of human life, including education, science, business, leisure time, entertainment, government, and health care. Human life is greatly dependent on these systems’ efficiency and performance. The HSI conference has been prepared as a platform for exchanging ideas, knowledge, skills and experiences in interactions between man and these systems. The HSI conference series has become the very important international conference in the field of Human System Interactions, human system science and engineering, human factors in large complex systems, human space computing and cyberphysical systems, human environment interactions, and social‐technical systems. This 14th international conference on Human System Interaction will be held in Gdańsk from the 8th to 10th July 2021. The conference will cover the theory, design and application of human‐system interactions in the areas of science, education, business, industry, services, humanity, environment, health, and government. Aside from the regular presentations, the conference will include keynote addresses from speakers who work both in industry and academia, and expects to attract more than 120 participants. Prospective authors are invited to submit papers on any of the topics listed below: